This article focuses on the critical importance of secure land tenure for both local and foreign investment, particularly in the Sub-Saharan African region, with Ghana as a case study. It emphasizes the positive impact of land tenure security on credit use, collateral value, efficient land transfer, reduced disputes, and increased productivity. Despite various challenges in Ghana's land sector, recent Supreme Court rulings on a generational land dispute involving the Numo Nmashie Family have far-reaching implications for land tenure security and investment in the country. The legal saga dates back to 1966 when the government acquired a significant land parcel, leading to a disputed Court of Appeal decision in 1982. The recent Supreme Court ruling overturned this decision, highlighting fraudulent information and directing the Lands Commission to rectify registrations. The consequences of this ruling are multifaceted and include tenure insecurity, tenancy transitions, legal obligations, the possibility of evictions or negotiations, financial obligations, investment caution, economic impact, legal challenges, disputes, community and social impact, and the potential need for government intervention and regulation. With emphasis on wide-ranging implications for existing tenants, residents, businesses, and the broader socio-economic landscape, the article underscores the need for careful consideration of legal and economic aspects in navigating the aftermath of the Supreme Court ruling.